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Watson, a businessman descended mostly from colonial English immigrants to America. He was part of a distributed group of researchers who were making use of the viruses that infect bacteriacalled bacteriophages. Importantly, the members of the Phage Group sensed that they were on the path to discovering the physical nature of the gene.
InWatson took a course with Felix Haurowitz that included the conventional view of that time: Watson's research project involved using X-rays to inactivate bacterial viruses.
Watson, however, wanted to explore the structure of DNA, and his interests did not coincide with Kalckar's. After obtaining some results from his phage and other experimental research  conducted at Indiana University, Statens Serum Institut DenmarkCSHL, and the California Institute of TechnologyWatson now had the desire to learn to perform X-ray diffraction experiments so he could work to determine the structure of DNA.
That summer, Luria met John Kendrew and he arranged for a new postdoctoral research project for Watson in England. Nearer Secret of Life. Oughton were some of the first people in April to see the model of the structure of DNAconstructed by Crick and Watson; at the time, they were working at Oxford University 's Chemistry Department.
According to the late Beryl Oughton, later Rimmer, they all travelled together in two cars once Dorothy Hodgkin announced to them that they were off to Cambridge to see the model of the structure of DNA. Watson subsequently presented a paper on the double-helical structure of DNA at the 18th Cold Spring Harbor Symposium on Viruses in early Junesix weeks after the publication of the Watson and Crick paper in Nature.
Many at the meeting had not yet heard of the discovery. Watson, Crick, and Wilkins were awarded the Nobel Prize in Physiology or Medicine in for their research on the structure of nucleic acids.
His work at Harvard focused on RNA and its role in the transfer of genetic information. He championed a switch in focus for the school from classical biology to molecular biologystating that disciplines such as ecologydevelopmental biologytaxonomyphysiologyetc. Watson continued to be a member of the Harvard faculty untileven though he took over the directorship of Cold Spring Harbor Laboratory in His most notable achievements in his two decades at Harvard may be what he wrote about science, rather than anything he discovered during that time.
His third textbook was Recombinant DNA, which described the ways in which genetic engineering has brought much new information about how organisms function. The textbooks are still in print.
Watson's original title was to have been "Honest Jim", in that the book recounts the discovery of the double helix from Watson's point of view and included many of his private emotional impressions at the time. Some controversy surrounded the publication of the book.
Watson's book was originally to be published by the Harvard University Pressbut Francis Crick and Maurice Wilkins objected, among others. Watson's home university dropped the project and the book was commercially published.
Between andthe Watsons' two sons were born, and bythe young family made Cold Spring Harbor their permanent residence. Watson served as the laboratory's director and president for about 35 years, and later he assumed the role of chancellor and then Chancellor Emeritus. In his roles as director, president, and chancellor, Watson led CSHL to articulate its present-day mission, "dedication to exploring molecular biology and genetics in order to advance the understanding and ability to diagnose and treat cancers, neurological diseases, and other causes of human suffering.
He is credited with "transforming a small facility into one of the world's great education and research institutions. Initiating a program to study the cause of human cancer, scientists under his direction have made major contributions to understanding the genetic basis of cancer.
Watson was opposed to Healy's attempts to acquire patents on gene sequences, and any ownership of the "laws of nature. InJames Watson became the second person  to publish his fully sequenced genome online,  after it was presented to him on May 31,by Life Sciences Corporation  in collaboration with scientists at the Human Genome Sequencing Center, Baylor College of Medicine.
Watson was quoted as saying, "I am putting my genome sequence on line to encourage the development of an era of personalized medicinein which information contained in our genomes can be used to identify and prevent disease and to create individualized medical therapies". For example, type 2 diabetes is usually thought to be caused by oxidation in the body that causes inflammation and kills off pancreatic cells.
Watson thinks the root of that inflammation is different: One critical response was that the idea was neither new nor worthy of merit, and that The Lancet published Watson's paper only because of his name. Moore and Joan Steitz.Writers and Editors, linking writers and editors to resources (including each other), markets, clients, and fans; maintained by Pat McNees, writer, personal and organizational historian, journalist, editor.
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